Table 3. Electroencephalographic Parameters after Intravenous Infusion of γ-Hydroxybutyric Acid for the Hypovolemic and Control Groups

Results are expressed as mean ± SD.

GHB =γ-hydroxybutyric acid (390 mg · kg⁻¹· 5 min⁻¹); E⁰= baseline value of the electroencephalographic parameter; E^max= maximal attainable depression, measured after the second infusion of 90 mg · kg⁻¹· min⁻¹until 1 s of isoelectric electroencephalogram; EC⁵⁰= GHB effect site concentration when 50% of maximum is reached; n = shape factor; k^e0= first-order rate constant; t^1/2k^e0= half-life of the distribution from the central compartment to the effect site.