Fig. 3. Interaction between the baroreceptor and Bezold–Jarisch reflexes (BJRs) in blood pressure regulation. Decreased activity of the afferent limb of the BJR results in decreased firing of the afferent fibers of the BJR. This leads to a release of vasomotor inhibition with augmented medullary outflow and a consequent increase in blood pressure. However, with the baroreceptor reflex present, this increased blood pressure response is attenuated and the expected effect of withdrawal of BJR activity does not occur and there is no change in systemic blood pressure.