Fig. 2. Dose–response relationship of isoflurane and halothane. Force expressed as a percentage of the control in mean ± SD (n = 3–24). Isoflurane at 3 and 5% (A ) and halothane at 1, 2, and 3% (B ) decreased pCa-induced force in a dose-dependent manner. However, the decrease was not statistically significant between 3 and 5% isoflurane.