American Society of Anesthesiologists

Fig. 8. The effects of the phosphatidylinositol-3 (PI3) kinase inhibitor LY294002 (50 μm) on preconditioning neuroprotection with 1.5% isoflurane in the CA1 region. Isofl PC = slices preconditioned with isoflurane 24 h before oxygen–glucose deprivation (OGD); PC + LY294002 = cultures preconditioned with isoflurane in the presence of the PI3kinase inhibitor. * Reduction in cell death ( P < 0.05) compared with nonpreconditioned cultures. The number of cultures in each group was 6–10.

Fig. 8. The effects of the phosphatidylinositol-3 (PI³) kinase inhibitor LY294002 (50 μm) on preconditioning neuroprotection with 1.5% isoflurane in the CA1 region. Isofl PC = slices preconditioned with isoflurane 24 h before oxygen–glucose deprivation (OGD); PC + LY294002 = cultures preconditioned with isoflurane in the presence of the PI³kinase inhibitor. * Reduction in cell death ( P < 0.05) compared with nonpreconditioned cultures. The number of cultures in each group was 6–10.

This Feature Is Available To Subscribers Only