Fig. 4. Volatile anesthetic sensitivity of KCNK5. (A ) Whole-cell currents of KCNK5 cRNA-injected oocytes perfused with either frog Ringer’s solution (FR) or FR with halothane (270 μm). (B ) Concentration-dependence of halothane and isoflurane potentiation of KCNK5 currents as quantified by the normalized response. Four to nine oocytes were studied in each treatment group.