Fig. 2. Normalized current-voltage (I-V) curves of Ca²⁺currents evoked with a 70 ms pulse from a holding potential of −80 mV to test potentials between −80 mV and +60 mV in mice carrying the 118AA (A ) and 118GG (C ) alleles. The current amplitude was measured 10 ms after the onset of the test pulse and normalized to the amplitude at −15 mV. The data in A  and C  represent the mean (± SEM) Ca²⁺current amplitude for each test potential. The number of neurons depicted in A  is 58 for test potentials from −80 to −40 mV, 36 for −35 mV, 57 for +45 to +55 mV and 55 for +60 mV. In C , the number of neurons shown is 56 for all test potentials, except for −35 mV, where 42 recordings were acquired. The Ca²⁺current traces in B  and D  correspond to a sensory neuron isolated from 118AA and 118GG allele carriers, respectively. The currents were elicited from a holding potential of −80 mV to the indicated test potentials applied every 3 s.