![Fig. 1. Calculation of the magnitude of offset analgesia (OA) relative to peak effect (ΔeVASC), where eVAS = electronic visual analog score, ΔeVAS = the decrease in eVAS from peak eVAS value to the eVAS nadir after the 1°C decrease of the test stimulus, and ΔeVASC= ΔeVAS corrected for the value of the peak eVAS (ΔeVASC= [ΔeVAS/(peak eVAS)]*100). (A ) Peak eVAS = a; reduction in eVAS after the 1°C decrease in noxious heat stimulation (ΔeVAS) = b; ΔeVASC= (b/a)*100% = 100% because a = b. (B ) Peak eVAS = a; ΔeVAS = c; ΔeVASC= (c/a)*100% = 75% because c = 0.75a. (C ) Peak eVAS = a; ΔeVAS = d; ΔeVASC= (d/a)*100% = 50% because d = 0.5a.](https://asa2.silverchair-cdn.com/asa2/content_public/journal/anesthesiology/115/5/10.1097_aln.0b013e31822fd03a/4/30ff1.png?Expires=1716634993&Signature=H8hi~hkRXI8l3rH5UPTyWbK7V5rnbEQtCXpJ9eHZwXd9NjQ7NpPqAdcYyoo~bvYPpJRdZvfvv8ThmcSTHuaEFAp36fwiTE5EsPaoRUYRZyjG0T76qeCDqPa3PJafy1kLuvseQ8r1QvE5Esd8eKtKeBc8DUAvjSSYcUPAhQp~IOThFxB08xHUTgKb2u7rm9M-H55uK2uEzKMVHTYvcPd8h1NJmSx2K6bMPz0fZyfgmn7U9HUaesZQH3neLw9Muu6QieVx-8CXGkuA9usluADqAEJMU5uyjCOuYouwDLFqXcw1RssuTv0ZGyQIhXa~QS2auQAMMy16g4SGbLpUJHAveg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Fig. 1. Calculation of the magnitude of offset analgesia (OA) relative to peak effect (ΔeVASC), where eVAS = electronic visual analog score, ΔeVAS = the decrease in eVAS from peak eVAS value to the eVAS nadir after the 1°C decrease of the test stimulus, and ΔeVASC= ΔeVAS corrected for the value of the peak eVAS (ΔeVASC= [ΔeVAS/(peak eVAS)]*100). (A ) Peak eVAS = a; reduction in eVAS after the 1°C decrease in noxious heat stimulation (ΔeVAS) = b; ΔeVASC= (b/a)*100% = 100% because a = b. (B ) Peak eVAS = a; ΔeVAS = c; ΔeVASC= (c/a)*100% = 75% because c = 0.75a. (C ) Peak eVAS = a; ΔeVAS = d; ΔeVASC= (d/a)*100% = 50% because d = 0.5a.
