Fig. 3. Morphometric analysis of mitochondria in the perikaryon of pyramidal subicular neurons of 21-day-old rats. (A ) Mitochondria in the experimental neurons occupy significantly more cytoplasmic soma than do those in controls (22.5%vs.  13.44%, *P < 0.05) (n = 15 neurons per group from 3 animals each). (B ) In experimental animals, mitochondrial density, presented as the number of mitochondria per unit area (μm²) of cytoplasmic soma, is significantly lower in pyramidal neurons than that in controls (*P < 0.05, n = 15 neurons per group from 3 control and 3 experimental pups; control and experimental pups were litter-matched).