Fig. 6. Morphometric analysis of mitochondria in presynaptic neuronal terminals in subicular neuropils of 21-day-old rats. (A ) Morphometric analysis of the area of mitochondrial profiles shows that experimental mitochondrial profiles were approximately 30% larger than that of a control group (*P < 0.05) (n = 30 photo frames obtained from 5 control pups; n = 45 photo frames obtained from 5 experimental pups; control and experimental pups were litter-matched; total of three different litters were used). (B ) There is no difference between control and experimental subiculi with regard to the areas of mitochondria-containing presynaptic nerve terminals (n = 30 photo frames obtained from 5 control pups; n = 45 photo frames obtained from 5 experimental pups; control and experimental pups were litter-matched; total of three different litters were used). (C ) The calculated mitochondrial index (ratio between mitochondrial area and mitochondria-containing presynaptic area) was significantly higher in experimental subicular neuropils (*P < 0.05) than in control neuropils.