Fig. 1.
Probability of 30-day mortality based on multivariable modeling is modified by the number of significant comorbidity risk factors, ranging from none (0) to 5. The comorbidities are low body weight (less than 5 kg), American Society of Anesthesiologists Physical Status III or higher, preoperative sepsis, inotropic support, and ventilator dependence. The impact of intrinsic surgical complexity risk on 30-day mortality is magnified among patients with a greater number of the five comorbidities.