Modeled trajectories of recovery from mechanical hypersensitivity after partial spinal nerve ligation (pSNL) in rats treated with dopamine β-hydroxylase (DβH)-saporin or control immunoglobulin G (IgG)-saporin 14 days before surgery. (A) Longitudinal behavioral measurements of mechanical paw withdrawal thresholds from the ipsilateral paw of individual rats modeled using growth curve analysis were best fit to a linear function described by an intercept (modeled withdrawal threshold immediately after pSNL surgery) and slope (linear rate of change in withdrawal threshold after pSNL surgery). (B) Group trajectories depict the mean fit for all the animals within each treatment group with 95% CIs indicated by shading.