Fig. 3.
Scattergrams displaying medians with quartiles for: (A) grading of intrathecal mass (0 to 4), and (B) rank ordering from least (rank 1) to greatest severity of intrathecal (IT) mass. For analysis, IT morphine + subcutaneous (SQ) saline was merged with IT morphine alone and IT saline + SQ naltrexone was merged with IT saline. The IT mass score for IT morphine with and without naltrexone were not different from each other but were significantly greater than that for IT saline. Mass scores for IT DMT-DALDA and IT PZM21, like saline, were significantly less than those for IT morphine. Similar results were observed with the blind ordering of the ranking of the masses (from least to greatest). Group comparisons employed a Kruskal–Wallace nonparametric one-way ANOVA and Dunn post hoc comparison. Exact P values are presented.