Fig. 2.
Fractional changes in the measured physiologic parameters at the time of desaturation (time zero) and during the 15-min recovery phase. Values are displayed as a fraction of predrug baseline values. Values are displayed as means ± SD. Statistical comparisons were only performed between baseline, nadir, and after 15-min of recovery, and the statistical results are summarized in table 1. Note the close correlation between changes in the pupil reflex and pupil area. BP = blood pressure; CO2 = carbon dioxide; NPi = neurologic pupil index.