Brain mitochondrial metabolism in neonatal and adult mice. (A–D) Overall lower oxygen consumption rate (A), basal respiration (B), adenosine diphosphate (ADP) respiration (C), and maximal respiration (D) in the hippocampus of neonatal mice of both sexes than female reference group mice (n = 6, Student’s t test). (E–H) Overall lower oxygen consumption rate (E), basal respiration (F), ADP respiration (G), and maximal respiration (H) in the hippocampus of neonatal mice of both sexes than male reference group mice (n = 6, Student’s t test). The data are presented as means ± SD. All data are quantified and expressed as real numbers compared with reference group mice (adult mice). Student’s t test was used. ***P < 0.001.