American Society of Anesthesiologists

Fig. 2.

$Relationship between lowest blood pressure values and myocardial injury. Univariable and multivariable relationship between myocardial injury and lowest blood pressure for a cumulative 5 min for each of four blood pressure components. (A) Estimated probability of myocardial injury from a univariable moving-window with a bin width of 10% of the data; (B) Multivariable logistic regression smoothed by restricted cubic spline with 3 knots at 10th, 50th, and 90th percentiles of given blood pressure component. Multivariable models adjusted for covariates in table 1. Based mainly on the multivariable plots, blood pressure component thresholds of 90 mmHg for systolic blood pressure, 65 mmHg for mean arterial pressure (MAP), 50 mmHg for diastolic blood pressure (DBP), and 35 mmHg for pulse pressure (PP) were visual change-points associated with increasing odds of myocardial injury. Histogram at the bottom of each graph shows the fraction of patients at each lowest blood pressure value. The blue lines in (A) and smoothed lines with 95% confidence bands in (B) indicate estimated probability of myocardial injury as a function of the lowest 5 min of each component. MINS, myocardial injury after noncardiac surgery; SBP, systolic arterial pressure.$

Relationship between lowest blood pressure values and myocardial injury. Univariable and multivariable relationship between myocardial injury and lowest blood pressure for a cumulative 5 min for each of four blood pressure components. (A) Estimated probability of myocardial injury from a univariable moving-window with a bin width of 10% of the data; (B) Multivariable logistic regression smoothed by restricted cubic spline with 3 knots at 10th, 50th, and 90th percentiles of given blood pressure component. Multivariable models adjusted for covariates in table 1. Based mainly on the multivariable plots, blood pressure component thresholds of 90 mmHg for systolic blood pressure, 65 mmHg for mean arterial pressure (MAP), 50 mmHg for diastolic blood pressure (DBP), and 35 mmHg for pulse pressure (PP) were visual change-points associated with increasing odds of myocardial injury. Histogram at the bottom of each graph shows the fraction of patients at each lowest blood pressure value. The blue lines in (A) and smoothed lines with 95% confidence bands in (B) indicate estimated probability of myocardial injury as a function of the lowest 5 min of each component. MINS, myocardial injury after noncardiac surgery; SBP, systolic arterial pressure.

This Feature Is Available To Subscribers Only