T0901317 down-regulated liver X receptor (LXR) α expression in the spinal dorsal horn, and this effect was prevented by aminoglutethimide. Bands show the expression of LXRα and β-actin in the five groups, as indicated. Histograms show the expression of LXRα and β-actin in the above groups (n = 5/group). ***P < 0.001 compared with dimethyl sulfoxide (DMSO)–treated sham group. ###P <0.001 compared with DMSO-treated spared nerve injury (SNI) group. $$$P < 0.001 compared with T0901317-treated SNI group.