Fig. 8. Circadian variations of the effects of pancuronium in rats anesthetized with althesin. From Bruguerolle B: General concepts and new trends in chronopharmacology, Biologic Clocks: Mechanisms and Applications. Proceedings of the International Congress on Chronobiology. Paris, 1977. Edited by Touitou Y. Amsterdam, Elsevier, 1998, pp 7–11. Used with permission.