Fig. 1. A recording of evoked twitch (at 0.15 Hz) and train-of-four (2 Hz for 2 s every 10 s) of the adductor pollicis in an anesthetized human volunteer. AV430A (0.4 mg/kg) was given intravenously at the arrow . Time scale (minutes) at top. Note change of time scale and change of evoked response from single twitch to train-of-four at minute 7. Onset of block is 80 s. Recovery to train-of-four of 95% is 13.5 min.