Figure 1. Percentage changes of pulmonary arterial pressure and systemic arterial pressure during inhalation of nitric oxide, zaprinast, or both aerosols. NO = nitric oxide; ZAP = zaprinast; PAP = pulmonary arterial pressure; SAP = systemic arterial pressure. n = 8 in groups of NO 5, NO 20, ZAP 10, ZAP 20. n = 6 in groups of ZAP 30, NO5/Zap10, NO20/Zap10. n = 4 in the ZAP 50 group. Values are reported as means +/- SD. *Significant reduction from the values at pulmonary hypertension (P < 0.05). #Significantly different from the value at NO 5 (P < 0.05) and from ZAP10 (P < 0.01).