Figure 2. Duration of the vasodilating response to inhaled NO, aerosolized zaprinast, or both. NO = nitric oxide; ZAP = zaprinast. n = 8 in groups of NO 5, NO 20, ZAP 10, ZAP 20. n = 6 in groups of ZAP 30, NO5/Zap10, NO20/Zap10. n = 4 in the ZAP 50 group. Values are reported as means +/- SD. The duration of the vasodilation induced by zaprinast inhalations was greater than that induced by inhaled NO. *Significantly differs from the values at the same NO concentration without zaprinast (P < 0.001) and from the value at ZAP10 (P < 0.001). #Significantly different from the values at both NO concentrations (P < 0.01).