Figure 2. Effects of 5 [micro sign]M 2-amino-5-phosphonopentanoic acid (AP-5) on spontaneous action potential firing of a neocortical neuron. The recording was carried out at room temperature. (A) Spike rates and (B) corresponding original recordings. Mean firing rates were 7.83 Hz before (control), 3.18 Hz during (AP-5), and 9.59 Hz after (wash) treatment.