Fig. 10. Strychnine sensitivity is increased in cords from −/− mice. (A ) Glycine inhibition is more pronounced in cords from −/− mice than +/+, as evidenced by a significantly (P < 0.05) greater increase in population excitatory postsynaptic potential (pEPSP) in the presence of strychnine (400 nm) in the former. (B  and C ) The interaction between glycine receptors and enflurane effects was probed by a protocol similar to that shown for GABA^Areceptors in figure 9, with strychnine (400 nm) in the place of bicuculline. However, glycine receptor block did not significantly attenuate the depressant effects of enflurane on this response in either population, although there was a tendency in that direction, and there were no differences between +/+ and −/− cords in this respect. Data points are means of four experiments; error bars are SEM.