Fig. 3. [¹⁸F]FECNT uptake in a rhesus monkey during low (solid symbols) and then high (open symbols) isoflurane anesthesia. Typical of these experiments, the uptake is greater and washout faster for the high anesthetic state. The dashed lines connecting the cerebellar data (squares) are only to guide the eye. The solid lines under the putamen data (circles) are the reference tissue model results using the cerebellum as the reference region. Binding potentials determined from the model are 1.78 and 0.32 for the low and high anesthetic levels, respectively.