Fig. 1. (A ) Influence of mastoparan (10−8, 10−6m) on pial small artery and arteriole diameter before (control), after FPI, after FPI with indomethacin (5 mg/kg, iv) pretreatment, after FPI with NS398 (10−4m) pretreatment, and after FPI with SODCAT (1000 and 10,000 U/kg, iv) pretreatment in newborn pigs. (B ) Influence of mastoparan on pial small artery and arteriole diameter before (control), after FPI, after FPI with indomethacin pretreatment, after FPI with NS398 pretreatment, and after FPI with SODCAT pretreatment in juvenile pigs (n = 6). Pial small artery and arteriole diameters were 145 ± 6 and 70 ± 4 μm at baseline and 120 ± 5 and 54 ± 4 μm after FPI. *P < 0.05 versus corresponding control value; +P < 0.05 versus corresponding nontreated FPI value; #P < 0.05 versus corresponding newborn value.
