Fig. 2. (A ) Influence of mastoparan-7 (10−8, 10−6m) on pial small artery and arteriole diameter before (control), after FPI, after FPI with indomethacin (5 mg/kg, iv) pretreatment, after FPI with NS398 (10−4m) pretreatment, and after FPI with SODCAT (1,000 and 10,000 U/kg) pretreatment in newborn pigs. (B ) Influence of mastoparan-7 on pial small artery and arteriole diameter before (control), after FPI, after FPI with indomethacin pretreatment, after FPI with NS398 pretreatment, and after FPI with SODCAT pretreatment in juvenile pigs (n = 6). Pial small artery and arteriole diameters were 148 ± 6 and 68 ± 5 μm at baseline and 124 ± 5 and 52 ± 4 μm after FPI. *P < 0.05 versus corresponding control; +P < 0.05 versus corresponding nontreated FPI value; #P < 0.05 versus corresponding newborn value.