Fig. 4. S100B serum concentration time course after coiling (n = 53) or neurosurgery (n = 21) according to the initial World Federation of Neurological Surgeons (WFNS) (  A ) or Fisher (  B ) scores.  Left and  right figures in each panel represent S100B time course for good initial clinical scores (WFNS 1–2 or Fisher 1–3) and poor initial clinical scores (WFNS 3–5 or Fisher 4–5). All differences each day were significant (  P < 0.05).