Fig. 5. ( A ) S100B day 1 value according to the outcome at intensive care unit discharge ( left ) and at 6 months ( right ). * P < 0.03. For graphical reasons, two patients were excluded from the figures. The box plots summarize the distribution of points at each factor level. The ends of the box are the 25th and 75th quartiles. The line across the middle of the box identifies the median sample value. The whiskers extend from the ends of the box to the outermost data point that falls within the distances computed. Statistical analysis was performed with the totality of the patients. ( B ) S100B time course values according to outcome at discharge ( left ) and at 6 months ( right ). Black bars represent Glasgow outcome scale (GOS) scores of 1–3, gray bars represent GOS scores of 4, and the white bars represent GOS scores of 5 (both repeated measures P < 0.001).