Fig. 4. Effects of sevoflurane in the presence of 6.0 μg/kg acetylcholine on percentage changes in total lung resistance (R^L) and dynamic lung compliance (C^Dyn) in control (cigarette-sham;  A ), ovalbumin-sensitized (  B ), and chronic cigarette-smoking (  C ) groups. Data are expressed as mean ± SD (n = 6 each). *  P < 0.05  versus each control value without sevoflurane. MAC = minimum alveolar concentration. Sevoflurane significantly and substantially decreased R^Land increased C^Dynin a dose-dependent manner in both the control and ovalbumin-sensitized groups. The anesthetic had a smaller effect on these parameters in the chronic cigarette-smoking group.