Fig. 6. Concentration-response curves to isoflurane (1–4%) in the presence or absence of pretreatment of glibenclamide (1 μm), a selective adenosine triphosphate-sensitive potassium channel blocker, or iberiotoxin (100 nm), a selective calcium-activated potassium channel blocker, obtained in rat thoracic aortas without endothelium. Data are shown as mean ± SD and expressed as percent of maximal relaxation induced by papaverine (3 × 10−4m). * P < 0.05 between control rings and rings pretreated with glibenclamide. § P < 0.05 between control rings and rings pretreated with iberiotoxin. n refers to the number of rats from which the aortas were obtained.
