Fig. 2. Percentage of injured alveoli, tissue myeloperoxidase (MPO) activity, and lung tissue wet:dry weight ratio, in the left lower lobe of the different groups. Values shown are mean ± SD. The groups were as follows: I, nonischemic group, 3 h perfusion, n = 11; II, nonischemic group, 27 h perfusion, n = 11; III, ischemia–reperfusion, 3 h reperfusion, n = 11; IV, ischemia–reperfusion, 27 h reperfusion, n = 11; V, MRS3558 administered before reperfusion, 3 h of reperfusion, n = 6; and VI, MRS3558 administered before reperfusion, 27 h of reperfusion, n = 6. *  P < 0.01  versus groups III–VI. **  P < 0.05  versus groups I–IV. #  P < 0.05  versus the other groups.