Fig. 2. Pulmonary relative messenger RNA (mRNA) expression of Toll-like receptor (TLR) 4 and TLR2 after 4 h of mechanical ventilation. Mechanical ventilation resulted in enhanced relative mRNA expression of TLR4 ( P = 0.008) and TLR2 ( P = 0.0006) in lung tissue of wild-type mice (group VTLR4WT) compared with unventilated wild-type mice (group CTLR4WT). Data are expressed as median with 25th and 75 percentiles ( box ) and range ( whiskers ). *P < 0.05 compared with group C-WT.