Fig. 3. Observed and predicted ratios between the first and fourth twitch height after train-of-four stimulation (TOF ratio) after administration of rocuronium 0.6 mg/kg alone or followed by sugammadex administration at 3 min at the following doses: ( A ) 0.1 mg/kg, ( B ) 0.5 mg/kg, ( C and D ) 1 mg/kg, ( E and F ) 2 mg/kg, ( G and H ) 4 mg/kg, or ( I and J ) 8 mg/kg. The open circles and cross symbols represent the observed TOF ratios in calibration study 1 without and with sugammadex, respectively. The solid and dashed lines represent the population-predicted TOF ratio without and with sugammadex, respectively.