Fig. 1. Effect of anti-nerve growth factor (NGF) peptibody on guarding pain behavior caused by plantar incision. (A ) Cumulative pain score after anti-NGF treatment in rats that underwent only skin incision. ( B ) Cumulative pain score after anti-NGF treatment in rats that underwent skin, fascia, and muscle incisions. t = P < 0.05 versus baseline. * P < 0.05 and ** P < 0.01 versus vehicle, respectively.