Fig. 1. Schematic illustration depicting the experimental protocols used to determine myocardial infarct size in rabbits in vivo . Additional experiments were completed with geldanamycin, radicicol, and L-NAME alone. APC = anesthetic preconditioning; CON = control; GELD = geldanamycin; IPC = ischemic preconditioning; ISO = isoflurane; L-NAME = N -nitro-L-arginine methyl ester; RAD = radicicol.