Fig. 2. Concentration-dependent decreases in myocardial infarct size by isoflurane postconditioning (IsoPC) in wild-type mice subjected to 30 min of coronary occlusion followed by 2 h of reperfusion. (A ) Area at risk expressed as a percentage of left ventricle area; (B ) myocardial infarct size expressed as a percentage of area at risk. IsoPC was produced by 0.5, 1.0, or 1.5 minimum alveolar concentration of isoflurane (ISO0.5, ISO1.0, or ISO1.5) administered during the last 5 min of ischemia and first 3 min of reperfusion. *P < 0.05 versus control (n = 8–10 mice/group).