Fig. 5. (A ) Spectrograms calculated from etomidate-induced electrical brain activity monitored in wild-type (A ) and β3(N265M) mice (B ). The data in the left column  are obtained from the recordings in the hippocampus and the data on the right  from the prefrontal cortex. The time point of etomidate administration is indicated by the vertical white bars . In the wild type, etomidate strongly reduced the power in all frequency bands between 0.5 and 35 Hz in the hippocampus and prefrontal cortex. This effect is less pronounced in the mutant. (C ) Total power before and after etomidate injection in the wild-type and the β3(N265M) mutants. RoRR = recovery of righting reflexes.