Fig. 6. The highest dose of dexmedetomidine (120.6 μm [20 μg/kg]) studied caused sedative effects immediately after anesthesia that prolonged the time to resumption of righting reflex (RoRR) when compared with all other groups (  P < 0.005). There were no other significant differences in RoRR. Total anesthesia time and percent isoflurane were not different between groups (data not shown). * Statistical significance,  P < 0.005.