Fig. 3. Levels of interleukin (IL)-6 and cytokine-induced neutrophil chemoattractant (CINC)-3 in the lung homogenate of healthy animals (A and D ) and LPS-primed animals infused with aged erythrocytes (RBCs day 14), fresh erythrocytes (RBCs, day 0), or saline (B and E ; one-way analysis of variance followed by Dunnett's post hoc test). Additional experiments (C and F ) show the effect of infusion of supernatant (Sup) of aged erythrocyte blood products or washed (Wash) aged erythrocytes in lipopolysaccharide (LPS)-primed animals (Student t test). Data are presented as mean ± SEM. *P < 0.01. N = 6 per group.