Fig. 4. Behavioral studies show no change in sensitivity to induction of halothane anesthesia and no difference in emergence from halothane anesthesia in narcoleptic orexin/ataxin-3 mice, as compared with their wild-type control siblings. (  A ) Loss of righting reflex dose–response curves for orexin-deficient mice (  gray squares ) and wild-type siblings (  black triangles ). (  B ) Latency to return of righting reflex after termination of halothane anesthesia for orexin/ataxin-3 mice (  gray ) and wild-type control siblings (  black ). Data are mean ± SEM.