Fig. 11. Neurologic scores and infarct volume after 120 min of transient middle cerebral artery occlusion in sham, control (CON), YC-1(3-(50-hydroxymethyl-20-furyl)-1-benzylindazole, orexin-A (OXA), and orexin-A + YC-1 groups. Neurologic scores are presented as median (range); data for infarct volume are expressed as mean ± SD. Neurologic scores were evaluated at 24 h (A ) and at 72 h (B ) after reperfusion using the Garcia scoring system. (C ) Representative 2,3,5-triphenyltetrazolium chloride staining of the cerebral infarct in the rat brain at 72 h after reperfusion. (D ) Statistical analysis of the percentage of infarct volume was determined. *P < 0.05 versus control. †P < 0.05 versus orexin-A.