Fig. 3. Observed sugammadex plasma concentrations and simulated sugammadex plasma concentration for a typical subject plotted on a logarithmic scale: (A ) adult group, (B ) elderly group, and (C ) old-elderly group. Time 0 represents the time of sugammadex administration. Lower limit of quantification (LLOQ) values of less than 0.1 were plotted as follows: 0.05 (1/2 × LLOQ).