Fig. 1.  Distribution of excitatory amino acid carrier 1 (EAAC1) in the dorsal root ganglion and spinal cord. *Postsynaptic density. (A ) EAAC1 was expressed predominantly in small dorsal root ganglion neurons. (B ) EAAC1 immunoreactivity was distributed mainly in the superficial dorsal horn of the spinal cord. Scale bar, 200 μm. (C ) a–c : In the superficial dorsal horn, immunogold labeling for EAAC1 (arrows ) was associated with postsynaptic membrane, presynaptic (pre) membrane, and the extrasynaptic membrane of the axonal terminal and postsynaptic process. Scale bar, 200 nm. d–e : Immunogold labeling for EAAC1 (arrows ; 10 nm gold) was colocalized with that of calcitonin gene-related peptide (arrowheads ; 5 nm gold), which is concentrated in dense-core vesicles in axon terminals. pre = presynaptic terminal. Scale bar, 100 nm.