Fig. 6. Concurrent noxious stimulation attenuates ketamine-induced increase in cyclin D1 expression. (A ) Western blot from postnatal day 7 brain protein lysates demonstrates that intraplantar CFA regulates (B ) changes in cyclin D1 expression during exposure to ketamine (n = 4, *P < 0.05). Data are presented as mean ± SE. CFA = complete Freund's adjuvant; KET = ketamine.