Fig. 4. Effect of etomidate on fast γ-aminobutyric acid type A (GABAA,fast) inhibitory postsynaptic currents (IPSCs). ( A ) Representative recordings of miniature IPSCs under control conditions ( top traces ) and in the presence of etomidate 0.5 μm ( middle traces ) and 1.0 μm ( bottom traces ). ( B–D ) Analysis of etomidate effects on amplitude ( B ), interevent interval ( C ), and kinetics ( D ) of GABAA,fastminiature IPSCs (currents normalized to peak current) for the cell illustrated in panel A.