Fig. 5. Evaluation of cytokine-induced neutrophil chemoattractant-1 (CINC-1;  A ) and monocyte chemoattractant protein-1 (MCP-1;  B ) messenger RNA expression in lung tissue. Lung tissue was collected after 6 h in the four study groups (propofol–lipopolysaccharide [LPS], propofol–phosphate-buffered saline [PBS], sevoflurane [Sevo]–LPS, and Sevo–PBS). CINC-1– and MCP-1–specific real-time polymerase chain reactions were performed on random transcribed complementary DNA. *  P < 0.05  versus propofol–LPS. Propofol–LPS, propofol–PBS: Instillation of LPS or PBS intratracheally, followed by ventilation and sedation with propofol for 6 h. Sevo–LPS, Sevo–PBS: Instillation of LPS or PBS intratracheally, followed by ventilation and sedation with propofol for 2 h and with Sevoflurane for the following 4 h. Values are mean ± SD from n = 6 (LPS) and n = 4 (PBS) experiments.