Fig. 6. Transmission electron microscopic images of renal tubular injury in endotoxemic sheep. Exemplary presentation of renal tubules of endotoxemic sheep treated with 6% hydroxyethyl starch (HES) 130/0.4 (A ), 10% HES 200/0.5 (B ), or sole crystalloids (C ) (1,000-fold magnification each). Dissociation of epithelium from basal lamina (closed arrow ), vacuolar cell degeneration (open arrow ), edematous tubular epithelial cell organella (open arrowheads ), and intraluminal precipitation of proteins (dashed closed arrows ).