Fig. 2. Plasma levels of cytokines in patients with severe sepsis carrying 8 or fewer copies of DEFA1/DEFA3 (filled squares , n = 27) and those with more than 8 copies of DEFA1/DEFA3 (filled triangles , n = 17). The line represents the median plasma level of related cytokines. (A ) Tumor necrosis factor (TNF)-α, P = 0.017; (B ) interleukin (IL)-6, P = 0.030; (C ) interleukin (IL)-10, P = 0.029.