Fig. 5.  Effect of caspase-1 inhibitor Ac-YVAD-CMK on paw edema induced by paw surgery. (A ) Effect of two injections of Ac-YVAD-CMK on paw edema. The treatment style was the same as described in figure 2. Values are displayed as mean ± SEM, n = 6, *P < 0.05 or ***P < 0.001 compared with control group. (B ) Ac-YVAD-CMK injection was made at 24 h after paw incision. (C ) The photo shows paw edema 24 h after paw incision (arrow  indication).