Fig. 6. Pooled data evaluating the effect of dexamethasone dose on late pain scores (24 h) at rest compared with placebo. Data evaluated using a random effects model. Point estimate (95% CI) for overall effect was −0.49 (−0.67 to −0.31). Standardized mean difference for individual study represented by circle on Forrest plot with 95% CI of the difference shown as solid line. Larger sized circle and thicker 95% CI line denote larger sample size. The diamond represents the pooled estimate and uncertainty for the effects of low- (0.1 mg/kg or less), intermediate- (0.11–0.2 mg/kg), and high-dose (more than 0.2 mg/kg) dexamethasone, respectively. Sample heterogeneity as assessed by the I 2for the low-, intermediate- and high-dose grouping of studies was 0, 71, and 96, respectively.
