Fig. 2. (A–F ) Timecourse of ipsilateral paw withdrawal thresholds (PWTs) (mean ± 95% confidence limits) for the fed, fasted, fasted + normal saline (NS), fasted + dextrose (dex), fed + insulin (ins) and fed + ins + dex groups. Ipsilateral PWTs of rats with chronic postischemia pain were lower than that of the rats in the sham group on each testing day for rats in the fed and fasted + dex glycemic conditions, and on test days 2–7 and 21 for the fed + ins + dex glycemic condition (**P < 0.01, Tukey post hoc  test).